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Epidemiology Research Guide

Online resources for the study of epidemiology

Meta-Analysis (EPID 7310) Text book

Featured Meta Analysis

There has been enormous debate regarding the possibility of a link between childhood vaccinations and the subsequent development of autism. This has in recent times become a major public health issue with vaccine preventable diseases increasing in the community due to the fear of a 'link' between vaccinations and autism. We performed a meta-analysis to summarise available evidence from case-control and cohort studies on this topic (MEDLINE, PubMed, EMBASE, Google Scholar up to April, 2014)PMID:24814559

Taylor, L. E., Swerdfeger, A. L., & Eslick, G. D. (2014). Vaccines are not associated with autism: An evidence-based meta-analysis of case-control and cohort studies. Vaccine, 32(29), 3623-3629. doi:10.1016/j.vaccine.2014.04.085 [doi]

We conducted a systematic review and meta-analysis to determine whether omega-3 PUFA supplementation reduces the incidence of cardiovascular events and complications in adults with peripheral arterial disease.


We searched five electronic databases (MEDLINE, EMBASE, CENTRAL, Scopus and the International Clinical Trials Registry Platform) from inception to 6 December 2013 to identify randomized trials of omega-3 PUFA supplementation (from fish or plant oils) that lasted ≥12 weeks in adults with peripheral arterial disease


Enns, J. E., Yeganeh, A., Zarychanski, R., Abou-Setta, A. M., Friesen, C., Zahradka, P., & Taylor, C. G. (2014). The impact of omega-3 polyunsaturated fatty acid supplementation on the incidence of cardiovascular events and complications in peripheral arterial disease: A systematic review and meta-analysis. BMC Cardiovascular Disorders, 14, 70-2261-14-70. doi:10.1186/1471-2261-14-70 [doi]

Grey literature

Clinical Trials databases (NIH)

Research Registries


Matas Instruction documents

Helpful tools

The PubMed interface defaults to searching PubMed. Change it to MeSH to search the thesaurus to develop search terms.

Meta Analysis Worksheets

When complete, the Meta Analysis Worksheet can be used to document all the steps required to perform a meta analysis.  

Review databases

Practice Guidelines

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